Crystal agile methodology

crystal ribcage: a platform for probing real-time lung function at cellular resolution - nature methods

a fabricated transparent ribcage facilitates real-time analysis of whole-lung function down to cellular resolution.

the seventh blind test of crystal structure prediction: structure generation methods - pubmed

a seventh blind test of crystal structure prediction was organized by the cambridge crystallographic data centre featuring seven target systems of varying complexity: a silicon and iodine-containing molecule, a copper coordination complex, a near-rigid molecule, a cocrystal, a polymorphic small agro …

crystal methods methodology

alistair cockburn developed the crystal methods approach. his focus is on the people, interaction, community, skills, talents, and communications with the

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crystal methodology

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a robust crystal structure prediction method to support small molecule drug development with large scale validation and blind study - nature communications

crystal polymorphism plays an important role in pharmaceuticals, agrisciences and other industries. here the authors present an efficient and accurate crystal structure prediction method with large scale validation and blind test.

the crystal agile framework

the crystal agile framework emphasizes people rather than procedures, empowering teams to develop their solutions for each project. discover more with craft!

the seventh blind test of crystal structure prediction: structure ranking methods - centaur

university publications

crystal agile framework: know the basics | glossary

what is crystal agile framework? what are the pros & cons of the crystal agile framework, & when should you use it? we've explained everything here.

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what is the crystal agile framework? definition and key principles

crystal is an agile methodology for software development. it focuses on people and communications over processes and tools and is uniquely flexible around team types, criticality and project priority.

understanding crystal methodology: a simple guide for agile enthusiasts

crystal methodology is a flexible and collaborative approach to project management within the agile framework. developed by alistair cockburn, it offers a set of practices tailored to fit the unique needs of each project.

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sir92 – a program for automatic solution of crystal structures by direct methods

sir92 – a program for automatic solution of crystal structures by direct methods

what is the agile crystal methodology? | wrike agile guide

crystal methodology emphasizes individuals and interactions over processes and tools. here’s what you need to know about this framework.

someone asked: "why did you create the crystal methods and how exactly is… | alistair cockburn | 16 comments

someone asked: "why did you create the crystal methods and how exactly is it different from the scrum method" ... so i answered. | 16 comments on linkedin

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the seventh blind test of crystal structure prediction: structure generation methods

the results of the seventh blind test of crystal structure prediction are presented, focusing on structure generation methods.

crystal method

nadrian seeman, sb’66, uses dna not to study biology but as a building block for nano-tiny structures.

crystal clear: what is crystallisation and why should i use it? | opinion | research live

researchers can use crystallisation to uncover multiple aspects of reality and experience.

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achieving a good crystal system for crystallographic x-ray fragment screening - pubmed

the xchem facility at diamond light source offers fragment screening by x-ray crystallography as a general access user program. the main advantage of x-ray crystallography as a primary fragment screen is that it yields directly the location and pose of the fragment hits, whether within pockets of in …

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osmotic communication test - crystal methods - agile project management questions | trusted institute

practice osmotic communication questions. osmotic communication is a concept in crystal methods that describes the free flow of information within a project team. it emphasiz…

a robust crystal structure prediction method to support small molecule drug development with large scale validation and prospective studies

crystal polymorphism is an important and fascinating aspect of solid state chemistry with far reaching implications in the pharmaceuticals, agrisciences, nutraceuticals, battery and aviation industries. late appearing more stable polymorphs have caused numerous issues in the pharmaceutical industry. experimental polymorph screening can be very expensive and time consuming, and sometimes may miss important low energy polymorphs due to its inability to exhaust all crystallization conditions. in this paper, we report a crystal structure prediction (csp) method with unprecedented accuracy and efficiency, validated on a large and diverse dataset including 65 molecules with 135 experimentally found polymorphic forms. the method combines a novel systematic crystal packing search algorithm and the first use of machine learning force fields in a hierarchical crystal energy ranking. our method not only reproduces all the experimentally known polymorphs, but also suggests new low energy polymorphs yet to be discovered by experiment that might pose potential risks to development of the currently known forms of these compounds. in addition, we also demonstrate, in two prospective drug development projects, how the method was used to accelerate clinical formulation design and derisk downstream processing. the high accuracy, reliability, and efficiency of our method with large scale validations and prospective studies position it for routine molecular crystal structure prediction in drug development.

introduction to crystal methodology

read the full article, introduction to crystal methodology, written by the experts at mindset consulting, llc.

studying viscoelastic materials using quartz crystal resonator

viscoelastic materials are often encountered in nature from biological matter, such as microbes and mammalian cells to non-biological matter such as polymers and even metals. studying these materials is often challenging due to their complex physical properties and many widely used methods are limited in their portability, simplicity, and the possibility for system integration. quartz crystal microbalance (qcm) is a tool which overcomes these limitations and can be used to gain insights into complex physical phenomena. using piezoelectricity, qcm gives us information about the environment it has been submerged in through parameters such as resonance frequency and dissipation. this immensely versatile tool has been chosen to tackle the problems explored in this project. two unsolved problems in the area of viscoelastic materials were chosen as subjects of this investigation.the first explored subject is bacterial detection, which is challenging at point-of-care (poc) with traditional methods due to the requirement of, slow detection times, high cost, and a need for laboratory infrustructure. qcm gives the potential to overcome these issues and in addition allow for portable online integration. poc bacterial diagnostics is necessary due to the increasing of antimicrobial resistance (amr) with non-specific use of antibiotics. qcm has shown potential for clinical bacterial detection in recent studies. recently, the anharmonic detection technique (adt) was presented as promoising but is yet to be validated for diagnosis of infections in complex biological samples and antibiotic susceptibility testing (ast). in this study the adt methodology was investigated and refined, leading to improved bacterial binding to qcm surface and enhanced transduction. for the first time adt was used in a bacterial infection setting, by detecting the infectious e. coli o111 strain in biological urine, mimicking a urinary tract infection. detection was achieved at a sensitivity of 106 cells/ml within a 50-minute test time. additionally, initial ast measurements were demonstrated with penicillin antibiotic. the second problem is from the area of charge storage which key for renewable energy. qcm was used to study novel amine based electrolytes for aluminium batteries. aluminium as a battery material overcomes several issues faced with lithium, most importantly availability and recyclability. the development of suitable electrolytes is a key hindrance for aluminium ion-batteries. the electrolytes studied in this project, although exhibiting promising electrochemical properties, are experimentally challenging due to their viscoelastic properties and complex viscosity behaviour during redox cycles. it was shown, how through qcm study, it was possible to extract crucial insight about the nature of these electrolytes and assess their potential for battery application. while electrochemical qcm (eqcm) is an established method for electrolyte studies, the unsolved problem exists of in-situ mass transport measurement for electrolytes exhibiting significant viscosity changes throughout the redox cycle, such as the electrolytes encountered in this research. in this work a new methodology is presented to overcome this issue, by using a model combining resonance frequency and dissipation data. it was shown that it can be used for in-situ measurements and has the potential to be applied for different electrolytes and electroplating applications.

the crystal method

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crystal agile framework

what is the crystal framework for agile product development? here is a broad overview of this agile framework and its strengths and weaknesses.

strategic project management and the agile crystal method

the agile crystal methodology provides a unique flavor to the general agile approach to managing projects. this post defines what the agile crystal method is, key aspects of the mindset behind the crystal approach, strategic consideration, and impacts for project managers. what is the agile crystal method? crystal was introduced by alistair cockburn at ibm

crystal agile methodology: your guide to the crystal framework in agile

find out all you need to know about the crystal method in agile. also learn about the origin, functioning and principles of the crystal agile methodology.

crystal growth unit

we prepare high quality bulk single crystals for physics research using a variety of melt and solution growth techniques; we have excellent facilities for sample preparation and characterisation.

crystal methods

this article gives highlights about crystal methods. crystal methods is a family of methods to deliver projects.

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the crystal clear methodology explained | iapm

crystal clear combines agile project management with other lightweight pm methods. this approach puts the focus on people.

which agile method is best for your team? — stormboard

agile — it’s a common term in the business world, and it involves many different methodologies that can cater to any kind of team.

a crystal method

ucsb researchers unlock another piece of the puzzle that is crystal growth

agile methods: scrum, crystal, extreme programming-an overview

scrum, crystal, extreme programming: which is the most popular framework? how can you choose the agile method that’s right for your company?

adrenaline method crystal

an ideal addition to your method feeders, adrenaline’s method crystal additive is an effective way to create intense visual attraction, swirling a coloured fog through the water, and drawing fish into your swim, and over to your hookbait, ensuring t

crystal agile framework. what it is, how it works, examples.

the crystal agile framework is a set of principles and practices designed to help teams develop and deliver software faster and more efficiently. it focuses on collaboration, communication, and continuous improvement to help teams achieve their goals. with the crystal agile framework, teams can quickly adapt to changing requirements and deliver high-quality software.

branding methods | laser engraved & colour print | laser crystal

here at laser crystal, we offer 3 types of branding methods for our crystal awards, trophies and paperweights. discover more at laser crystal.

crystal clear methodology – custom web & mobile development company – new line technologies

crystal is a family of software development methodologies with a common genetic code, including: frequent delivery, personal communications and improvement through reflection. for each type of project there’s its own method of crystal. crystal clear is a lightweight, flexible methodology created by alistair cockburn in 2004. it is designed for small teams of 6-8 people […]

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the crystal method · album · 2014 · 11 songs

the hidden crystal method

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introduction to crystal methods (ii): crystal roles and responsibilities - weekly sharing - zentao

the crystal method is one of the most lightweight and flexible software development methods. it consists of crystal clear, crystal yellow, crystal red, and other agile methods with unique characteristics.

crystal | do you know the seven characteristics of the crystal method? - weekly sharing - zentao

crystal - crystal methodology is a series of agile methods established by alistair cockburn and jim highsmith. alistair cockburn refines the crystal methodology into crystal clear, crystal yellow, crystal orange, and crystal red. these crystal methodologies are divided according to the importance of the project and the size of the participants.

crystal methods overview - software development life cycle (sdlc) video tutorial | linkedin learning, formerly lynda.com

in this video, learn about crystal methods, a family of methodologies with common principles such as frequent delivery, close communication, reflective improvement, etc.

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crystal agile methodology: a guide to flexible software development - sixsigma.us

crystal agile methodology is a software development framework that prioritizes people, interactions, and skills over processes and tools.

crystal agile methodology in project management

find out what the crystal agile methodology is, who created it, when it's appropriate to use, and how the monday.com os work platform can help your team stay organized.

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explore the crystal method

a multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density - nature communications

building a ligand into a weak region of an electron density map of a protein is a subjective process. here, the authors present a new method to obtain a clear electron density for a bound ligand based on multi-crystal experiments and 3d background correction.

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